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Mass Spectrometry Facility

The Department of Chemistry and Biochemistry operates an in-house Mass Spectrometry facility to support research and teaching activities. Mass Spectrometry is a primary tool for structure elucidation, molecular weight determination and molecular formula confirmation for organic and biological materials. This family of techniques measures the masses of organic and biological molecules by creating gas phase ions from the analytes and manipulating those ions in electric and magnetic fields. Chemical structure may be probed by fragmenting molecular ions and mass measuring the resulting product ions. 
Ionization Techniques Available:
Electron Ionization (EI)
Chemical Ionization (CI)
Field Ionization/Field Desorption (FI/FD)
Electrospray Ionization (ESI)
Services Available:
Full Scan MS
Accurate Mass Measurement (HRMS)
Direct Infusion or HPLC ESI MS
Direct Insertion Probe EI, CI, FI/FD
Data Interpretation
Instrument Training



  1. High Resolution Time-of-Flight mass spectrometer »
    Campus Gov't/Academic Industry

    Used primarily for small organic analytes and low polarity materials.  The instrument is equipped with electron ionization (EI), chemical ionization (CI), and field ionization/field desorption (FI/FD) ion sources.  The instrument has a mass range up to 800m/z in EI, CI and FI modes and up to 4,000m/z in FD mode.  Accurate mass measurement (< 3 mDa) for elemental composistion confirmation is available in Ei, CI and FI modes.  The GCT Premier runs with an Agilent 7890 Gas Chromatograph with autosampler in "walk up" access mode when not operated in solids probe mode by facility staff.

  2. HP 5970 GC/MS »
    Campus Gov't/Academic Industry

    An HP 5970 GC/MS running in dedicated EI mode (mass range < m/z 550) is available for open access usage. The instrument is equipped with a J&W DB-5ms 30m GC column, with 0.25 mm ID and 0.25 µm film thickness.

  3. MALDI TOF Mass Spectrometer »
    Campus Gov't/Academic Industry

    The Bruker (Bruker Daltonics, Billerica, MA) Microflex LRF MALDI TOF mass spectrometer is used for the analysis of a broad range of compounds including small molecules, peptides, proteins, nucleic acids, and synthetic polymers.