The Covaris M220 is designed for Next-Gen Sequencing applications requiring fragment sizes between 150bp and 5kb. It is used to mechanically shear nucleic acids into smaller fragments by focused ultrasonic waves. It is the recommended instrument to mechanically shear nucleic acids in Illumina protocols.
It takes both microTUBE (50ul) and miniTUBE (130 ul).
Trained users will have keycard access to the lab and will be able to book and use the analytical instruments. For ease of management, molecular biology instruments located in the BNL are also part of the Analytical core. Researchers can also engage BNL staff to perform basic molecular biological experiments such as recombinant protein expression. Cost will be on a project-by-project basis and will include staff man-hours, materials used and instrument recharges.