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Gel Permeation Chromatography (GPC) - Aqueous

Instrument types

Determine the molecular weight of your water soluble polymer with Gel Permeation Chromatography (GPC) using a Waters 2695 Separations module. Gel Permeation Chromatography (GPC) is a type of liquid chromatography method that separates molecules on the basis of hydrodynamic size (not Mw). The large molecules move more rapidly through the GPC column, while the smaller molecules reside longer on the column causing separation. Using GPC, you can determine the number average molecular weight, weight average molecular weight, Z weight average molecular weight, and the most fundamental characteristic of a polymer, its molecular weight distribution (PDI= Mw/Mn).

Technical Primary Contact:
Rachel Behrens

Access Procedure: 
Users of the MRL Synthesis and Characterization Laboratory are required to go through two levels of training before they are authorized to perform data collection independently. The training consists of
  • General lab safety training, provided by the UCSB Environmental Health & Safety Department (EH&S).
  • Instrument training, conducted by development engineer or an authorized user delegated by the development engineer.